A Placebo-Controlled Trial of AQW051 in Patients With Moderate to Severe Levodopa-Induced Dyskinesia.
Identifieur interne : 000045 ( France/Analysis ); précédent : 000044; suivant : 000046A Placebo-Controlled Trial of AQW051 in Patients With Moderate to Severe Levodopa-Induced Dyskinesia.
Auteurs : Claudia Trenkwalder [Allemagne] ; Daniela Berg [Allemagne] ; Olivier Rascol [France] ; Karla Eggert [Allemagne] ; Andres Ceballos-Baumann [Allemagne] ; Jean-Christophe Corvol [France] ; Alexander Storch [Allemagne] ; Lin Zhang [États-Unis] ; Jean-Philippe Azulay [France] ; Emmanuel Broussolle [France] ; Luc Defebvre [France] ; Christian Geny [France] ; Michal Gostkowski [États-Unis] ; Fabrizio Stocchi [Italie] ; Christine Tranchant [France] ; Pascal Derkinderen [France] ; Franck Durif [France] ; Alberto J. Espay [États-Unis] ; Andrew Feigin [États-Unis] ; Jean-Luc Houeto [France] ; Johannes Schwarz [Allemagne] ; Thérèse Di Paolo [Canada] ; Dominik Feuerbach [Suisse] ; Hans-Ulrich Hockey [Suisse] ; Judith Jaeger [États-Unis] ; Annamaria Jakab [Suisse] ; Donald Johns [États-Unis] ; Gurutz Linazasoro [Espagne] ; Paul Maruff [États-Unis] ; Izabela Rozenberg [Suisse] ; Judit Sovago [Suisse] ; Markus Weiss [Suisse] ; Baltazar Gomez-Mancilla [Suisse]Source :
- Movement disorders : official journal of the Movement Disorder Society [ 1531-8257 ] ; 2016.
Abstract
This phase 2 randomized, double-blind, placebo-controlled study evaluated the efficacy and safety of the nicotinic acetylcholine receptor α7 agonist AQW051 in patients with Parkinson's disease and levodopa-induced dyskinesia.
DOI: 10.1002/mds.26569
PubMed: 26990766
Affiliations:
- Allemagne, Canada, Espagne, France, Italie, Suisse, États-Unis
- Californie, Connecticut, Delaware, District de Giessen, District de Kassel, Hauts-de-France, Hesse (Land), Latium, Midi-Pyrénées, New Jersey, Nord-Pas-de-Calais, Occitanie (région administrative), Ohio, État de New York
- Cassel (Hesse), Lille, Marbourg, Rome, Toulouse
- Université Lille 2, Université Lille Nord de France
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pubmed:26990766Le document en format XML
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xml:lang="fr">Allemagne</country><wicri:regionArea>Paracelsus-Elena Hospital, Kassel</wicri:regionArea><placeName><region type="land" nuts="1">Hesse (Land)</region><region type="district" nuts="2">District de Kassel</region><settlement type="city">Cassel (Hesse)</settlement></placeName></affiliation></author><author><name sortKey="Berg, Daniela" sort="Berg, Daniela" uniqKey="Berg D" first="Daniela" last="Berg">Daniela Berg</name><affiliation wicri:level="3"><nlm:affiliation>German Parkinson Study Group, Marburg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>German Parkinson Study Group, Marburg</wicri:regionArea><placeName><region type="land" nuts="1">Hesse (Land)</region><region type="district" nuts="2">District de Giessen</region><settlement type="city">Marbourg</settlement></placeName></affiliation></author><author><name sortKey="Rascol, Olivier" sort="Rascol, Olivier" uniqKey="Rascol O" first="Olivier" last="Rascol">Olivier Rascol</name><affiliation wicri:level="3"><nlm:affiliation>Department of Clinical Pharmacology and Neurosciences, NeuroToul Excellence Center for Neurodegenerative Disorders, University UPS of Toulouse III, CIC-9302/INSERM UMR825, Hôpital Purpan - Pavillon Riser, Toulouse, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Clinical Pharmacology and Neurosciences, NeuroToul Excellence Center for Neurodegenerative Disorders, University UPS of Toulouse III, CIC-9302/INSERM UMR825, Hôpital Purpan - Pavillon Riser, Toulouse</wicri:regionArea><placeName><region type="region">Occitanie (région administrative)</region><region type="old region">Midi-Pyrénées</region><settlement type="city">Toulouse</settlement></placeName></affiliation></author><author><name sortKey="Eggert, Karla" sort="Eggert, Karla" uniqKey="Eggert K" first="Karla" last="Eggert">Karla Eggert</name><affiliation wicri:level="3"><nlm:affiliation>German Parkinson Study Group, Marburg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>German Parkinson Study Group, Marburg</wicri:regionArea><placeName><region type="land" nuts="1">Hesse (Land)</region><region type="district" nuts="2">District de Giessen</region><settlement type="city">Marbourg</settlement></placeName></affiliation></author><author><name sortKey="Ceballos Baumann, Andres" sort="Ceballos Baumann, Andres" uniqKey="Ceballos Baumann A" first="Andres" last="Ceballos-Baumann">Andres Ceballos-Baumann</name><affiliation wicri:level="3"><nlm:affiliation>German Parkinson Study Group, Marburg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>German Parkinson Study Group, Marburg</wicri:regionArea><placeName><region type="land" nuts="1">Hesse (Land)</region><region type="district" nuts="2">District de Giessen</region><settlement type="city">Marbourg</settlement></placeName></affiliation></author><author><name sortKey="Corvol, Jean Christophe" sort="Corvol, Jean Christophe" uniqKey="Corvol J" first="Jean-Christophe" last="Corvol">Jean-Christophe Corvol</name><affiliation wicri:level="1"><nlm:affiliation>NS PARK/FCRIN Network, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>NS PARK/FCRIN Network</wicri:regionArea></affiliation></author><author><name sortKey="Storch, Alexander" sort="Storch, Alexander" uniqKey="Storch A" first="Alexander" last="Storch">Alexander Storch</name><affiliation wicri:level="3"><nlm:affiliation>German Parkinson Study Group, Marburg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>German Parkinson Study Group, Marburg</wicri:regionArea><placeName><region type="land" nuts="1">Hesse (Land)</region><region type="district" nuts="2">District de Giessen</region><settlement type="city">Marbourg</settlement></placeName></affiliation></author><author><name sortKey="Zhang, Lin" sort="Zhang, Lin" uniqKey="Zhang L" first="Lin" last="Zhang">Lin Zhang</name><affiliation wicri:level="2"><nlm:affiliation>Department of Neurology, UC Davis MIND Institute, Sacramento, California, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Neurology, UC Davis MIND Institute, Sacramento, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Azulay, Jean Philippe" sort="Azulay, Jean Philippe" uniqKey="Azulay J" first="Jean-Philippe" last="Azulay">Jean-Philippe Azulay</name><affiliation wicri:level="1"><nlm:affiliation>NS PARK/FCRIN Network, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>NS PARK/FCRIN Network</wicri:regionArea></affiliation></author><author><name sortKey="Broussolle, Emmanuel" sort="Broussolle, Emmanuel" uniqKey="Broussolle E" first="Emmanuel" last="Broussolle">Emmanuel Broussolle</name><affiliation wicri:level="1"><nlm:affiliation>NS PARK/FCRIN Network, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>NS PARK/FCRIN Network</wicri:regionArea></affiliation></author><author><name sortKey="Defebvre, Luc" sort="Defebvre, Luc" uniqKey="Defebvre L" first="Luc" last="Defebvre">Luc Defebvre</name><affiliation wicri:level="1"><nlm:affiliation>NS PARK/FCRIN Network, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>NS PARK/FCRIN Network</wicri:regionArea><placeName><settlement type="city">Lille</settlement><region type="region" nuts="2">Hauts-de-France</region><region type="old region" nuts="2">Nord-Pas-de-Calais</region></placeName><orgName type="university" n="3">Université Lille 2</orgName><orgName type="institution" wicri:auto="newGroup">Université Lille Nord de France</orgName><placeName><settlement type="city">Lille</settlement><region type="region" nuts="2">Hauts-de-France</region><region type="old region" nuts="2">Nord-Pas-de-Calais</region></placeName><orgName type="university" n="3">Université Lille 2</orgName><orgName type="institution" wicri:auto="newGroup">Université Lille Nord de France</orgName></affiliation></author><author><name sortKey="Geny, Christian" sort="Geny, Christian" uniqKey="Geny C" first="Christian" last="Geny">Christian Geny</name><affiliation wicri:level="1"><nlm:affiliation>NS PARK/FCRIN Network, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>NS PARK/FCRIN Network</wicri:regionArea></affiliation></author><author><name sortKey="Gostkowski, Michal" sort="Gostkowski, Michal" uniqKey="Gostkowski M" first="Michal" last="Gostkowski">Michal Gostkowski</name><affiliation wicri:level="2"><nlm:affiliation>Center for Neurological Restoration, Cleveland Clinic, Cleveland, Ohio, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Neurological Restoration, Cleveland Clinic, Cleveland, Ohio</wicri:regionArea><placeName><region type="state">Ohio</region></placeName></affiliation></author><author><name sortKey="Stocchi, Fabrizio" sort="Stocchi, Fabrizio" uniqKey="Stocchi F" first="Fabrizio" last="Stocchi">Fabrizio Stocchi</name><affiliation wicri:level="3"><nlm:affiliation>Department of Neurology, Institute for Research and Medical Care, IROCS, Rome, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Neurology, Institute for Research and Medical Care, IROCS, Rome</wicri:regionArea><placeName><settlement type="city">Rome</settlement><region nuts="2">Latium</region></placeName></affiliation></author><author><name sortKey="Tranchant, Christine" sort="Tranchant, Christine" uniqKey="Tranchant C" first="Christine" last="Tranchant">Christine Tranchant</name><affiliation wicri:level="1"><nlm:affiliation>NS PARK/FCRIN Network, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>NS PARK/FCRIN Network</wicri:regionArea></affiliation></author><author><name sortKey="Derkinderen, Pascal" sort="Derkinderen, Pascal" uniqKey="Derkinderen P" first="Pascal" last="Derkinderen">Pascal Derkinderen</name><affiliation wicri:level="1"><nlm:affiliation>NS PARK/FCRIN Network, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>NS PARK/FCRIN Network</wicri:regionArea></affiliation></author><author><name sortKey="Durif, Franck" sort="Durif, Franck" uniqKey="Durif F" first="Franck" last="Durif">Franck Durif</name><affiliation wicri:level="1"><nlm:affiliation>NS PARK/FCRIN Network, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>NS PARK/FCRIN Network</wicri:regionArea></affiliation></author><author><name sortKey="Espay, Alberto J" sort="Espay, Alberto J" uniqKey="Espay A" first="Alberto J" last="Espay">Alberto J. Espay</name><affiliation wicri:level="2"><nlm:affiliation>Department of Neurology, James J. and Joan A. Gardner Family Center for Parkinson's Disease and Movement Disorders, University of Cincinnati Academic Health Center, Cincinnati, Ohio, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Neurology, James J. and Joan A. Gardner Family Center for Parkinson's Disease and Movement Disorders, University of Cincinnati Academic Health Center, Cincinnati, Ohio</wicri:regionArea><placeName><region type="state">Ohio</region></placeName></affiliation></author><author><name sortKey="Feigin, Andrew" sort="Feigin, Andrew" uniqKey="Feigin A" first="Andrew" last="Feigin">Andrew Feigin</name><affiliation wicri:level="2"><nlm:affiliation>Feinstein Institute for Medical Research, North Shore - LIJ Health System, Manhasset, New York, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Feinstein Institute for Medical Research, North Shore - LIJ Health System, Manhasset, New York</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation></author><author><name sortKey="Houeto, Jean Luc" sort="Houeto, Jean Luc" uniqKey="Houeto J" first="Jean-Luc" last="Houeto">Jean-Luc Houeto</name><affiliation wicri:level="1"><nlm:affiliation>NS PARK/FCRIN Network, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>NS PARK/FCRIN Network</wicri:regionArea></affiliation></author><author><name sortKey="Schwarz, Johannes" sort="Schwarz, Johannes" uniqKey="Schwarz J" first="Johannes" last="Schwarz">Johannes Schwarz</name><affiliation wicri:level="3"><nlm:affiliation>German Parkinson Study Group, Marburg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>German Parkinson Study Group, Marburg</wicri:regionArea><placeName><region type="land" nuts="1">Hesse (Land)</region><region type="district" nuts="2">District de Giessen</region><settlement type="city">Marbourg</settlement></placeName></affiliation></author><author><name sortKey="Di Paolo, Therese" sort="Di Paolo, Therese" uniqKey="Di Paolo T" first="Thérèse" last="Di Paolo">Thérèse Di Paolo</name><affiliation wicri:level="1"><nlm:affiliation>Neuroscience Research Unit, Centre de recherche du CHU de Québec, Québec, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Neuroscience Research Unit, Centre de recherche du CHU de Québec, Québec</wicri:regionArea><wicri:noRegion>Québec</wicri:noRegion></affiliation></author><author><name sortKey="Feuerbach, Dominik" sort="Feuerbach, Dominik" uniqKey="Feuerbach D" first="Dominik" last="Feuerbach">Dominik Feuerbach</name><affiliation wicri:level="1"><nlm:affiliation>Novartis Institutes for BioMedical Research, Basel, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Novartis Institutes for BioMedical Research, Basel</wicri:regionArea><wicri:noRegion>Basel</wicri:noRegion></affiliation></author><author><name sortKey="Hockey, Hans Ulrich" sort="Hockey, Hans Ulrich" uniqKey="Hockey H" first="Hans-Ulrich" last="Hockey">Hans-Ulrich Hockey</name><affiliation wicri:level="1"><nlm:affiliation>Novartis Institutes for BioMedical Research, Basel, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Novartis Institutes for BioMedical Research, Basel</wicri:regionArea><wicri:noRegion>Basel</wicri:noRegion></affiliation></author><author><name sortKey="Jaeger, Judith" sort="Jaeger, Judith" uniqKey="Jaeger J" first="Judith" last="Jaeger">Judith Jaeger</name><affiliation wicri:level="2"><nlm:affiliation>Albert Einstein College of Medicine, New York, NY, USA, and CognitionMetrics, LLC, Wilmington, Delaware, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Albert Einstein College of Medicine, New York, NY, USA, and CognitionMetrics, LLC, Wilmington, Delaware</wicri:regionArea><placeName><region type="state">Delaware</region></placeName></affiliation></author><author><name sortKey="Jakab, Annamaria" sort="Jakab, Annamaria" uniqKey="Jakab A" first="Annamaria" last="Jakab">Annamaria Jakab</name><affiliation wicri:level="1"><nlm:affiliation>Novartis Institutes for BioMedical Research, Basel, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Novartis Institutes for BioMedical Research, Basel</wicri:regionArea><wicri:noRegion>Basel</wicri:noRegion></affiliation></author><author><name sortKey="Johns, Donald" sort="Johns, Donald" uniqKey="Johns D" first="Donald" last="Johns">Donald Johns</name><affiliation wicri:level="2"><nlm:affiliation>Novartis Pharmaceuticals Corporation, East Hanover, New Jersey, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Novartis Pharmaceuticals Corporation, East Hanover, New Jersey</wicri:regionArea><placeName><region type="state">New Jersey</region></placeName></affiliation></author><author><name sortKey="Linazasoro, Gurutz" sort="Linazasoro, Gurutz" uniqKey="Linazasoro G" first="Gurutz" last="Linazasoro">Gurutz Linazasoro</name><affiliation wicri:level="1"><nlm:affiliation>Inbiomed, San Sebastian, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Inbiomed, San Sebastian</wicri:regionArea><wicri:noRegion>San Sebastian</wicri:noRegion></affiliation></author><author><name sortKey="Maruff, Paul" sort="Maruff, Paul" uniqKey="Maruff P" first="Paul" last="Maruff">Paul Maruff</name><affiliation wicri:level="2"><nlm:affiliation>CogState, Inc, New Haven, Connecticut, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>CogState, Inc, New Haven, Connecticut</wicri:regionArea><placeName><region type="state">Connecticut</region></placeName></affiliation></author><author><name sortKey="Rozenberg, Izabela" sort="Rozenberg, Izabela" uniqKey="Rozenberg I" first="Izabela" last="Rozenberg">Izabela Rozenberg</name><affiliation wicri:level="1"><nlm:affiliation>Novartis Institutes for BioMedical Research, Basel, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Novartis Institutes for BioMedical Research, Basel</wicri:regionArea><wicri:noRegion>Basel</wicri:noRegion></affiliation></author><author><name sortKey="Sovago, Judit" sort="Sovago, Judit" uniqKey="Sovago J" first="Judit" last="Sovago">Judit Sovago</name><affiliation wicri:level="1"><nlm:affiliation>Novartis Institutes for BioMedical Research, Basel, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Novartis Institutes for BioMedical Research, Basel</wicri:regionArea><wicri:noRegion>Basel</wicri:noRegion></affiliation></author><author><name sortKey="Weiss, Markus" sort="Weiss, Markus" uniqKey="Weiss M" first="Markus" last="Weiss">Markus Weiss</name><affiliation wicri:level="1"><nlm:affiliation>Novartis Institutes for BioMedical Research, Basel, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Novartis Institutes for BioMedical Research, Basel</wicri:regionArea><wicri:noRegion>Basel</wicri:noRegion></affiliation></author><author><name sortKey="Gomez Mancilla, Baltazar" sort="Gomez Mancilla, Baltazar" uniqKey="Gomez Mancilla B" first="Baltazar" last="Gomez-Mancilla">Baltazar Gomez-Mancilla</name><affiliation wicri:level="1"><nlm:affiliation>Novartis Institutes for BioMedical Research, Basel, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Novartis Institutes for BioMedical Research, Basel</wicri:regionArea><wicri:noRegion>Basel</wicri:noRegion></affiliation></author></analytic><series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title><idno type="eISSN">1531-8257</idno><imprint><date when="2016" type="published">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">This phase 2 randomized, double-blind, placebo-controlled study evaluated the efficacy and safety of the nicotinic acetylcholine receptor α7 agonist AQW051 in patients with Parkinson's disease and levodopa-induced dyskinesia.</div></front></TEI><affiliations><list><country><li>Allemagne</li><li>Canada</li><li>Espagne</li><li>France</li><li>Italie</li><li>Suisse</li><li>États-Unis</li></country><region><li>Californie</li><li>Connecticut</li><li>Delaware</li><li>District de Giessen</li><li>District de Kassel</li><li>Hauts-de-France</li><li>Hesse (Land)</li><li>Latium</li><li>Midi-Pyrénées</li><li>New Jersey</li><li>Nord-Pas-de-Calais</li><li>Occitanie (région administrative)</li><li>Ohio</li><li>État de New York</li></region><settlement><li>Cassel (Hesse)</li><li>Lille</li><li>Marbourg</li><li>Rome</li><li>Toulouse</li></settlement><orgName><li>Université Lille 2</li><li>Université Lille Nord de France</li></orgName></list><tree><country name="Allemagne"><region name="Hesse (Land)"><name sortKey="Trenkwalder, Claudia" sort="Trenkwalder, Claudia" uniqKey="Trenkwalder C" first="Claudia" last="Trenkwalder">Claudia Trenkwalder</name></region><name sortKey="Berg, Daniela" sort="Berg, Daniela" uniqKey="Berg D" first="Daniela" last="Berg">Daniela Berg</name><name sortKey="Ceballos Baumann, Andres" sort="Ceballos Baumann, Andres" uniqKey="Ceballos Baumann A" first="Andres" last="Ceballos-Baumann">Andres Ceballos-Baumann</name><name sortKey="Eggert, Karla" sort="Eggert, Karla" uniqKey="Eggert K" first="Karla" last="Eggert">Karla Eggert</name><name sortKey="Schwarz, Johannes" sort="Schwarz, Johannes" uniqKey="Schwarz J" first="Johannes" last="Schwarz">Johannes Schwarz</name><name sortKey="Storch, Alexander" sort="Storch, Alexander" uniqKey="Storch A" first="Alexander" last="Storch">Alexander Storch</name></country><country name="France"><region name="Occitanie (région administrative)"><name sortKey="Rascol, Olivier" sort="Rascol, Olivier" uniqKey="Rascol O" first="Olivier" last="Rascol">Olivier Rascol</name></region><name sortKey="Azulay, Jean Philippe" sort="Azulay, Jean Philippe" uniqKey="Azulay J" first="Jean-Philippe" last="Azulay">Jean-Philippe Azulay</name><name sortKey="Broussolle, Emmanuel" sort="Broussolle, Emmanuel" uniqKey="Broussolle E" first="Emmanuel" last="Broussolle">Emmanuel Broussolle</name><name sortKey="Corvol, Jean Christophe" sort="Corvol, Jean Christophe" uniqKey="Corvol J" first="Jean-Christophe" last="Corvol">Jean-Christophe Corvol</name><name sortKey="Defebvre, Luc" sort="Defebvre, Luc" uniqKey="Defebvre L" first="Luc" last="Defebvre">Luc Defebvre</name><name sortKey="Derkinderen, Pascal" sort="Derkinderen, Pascal" uniqKey="Derkinderen P" first="Pascal" last="Derkinderen">Pascal Derkinderen</name><name sortKey="Durif, Franck" sort="Durif, Franck" uniqKey="Durif F" first="Franck" last="Durif">Franck Durif</name><name sortKey="Geny, Christian" sort="Geny, Christian" uniqKey="Geny C" first="Christian" last="Geny">Christian Geny</name><name sortKey="Houeto, Jean Luc" sort="Houeto, Jean Luc" uniqKey="Houeto J" first="Jean-Luc" last="Houeto">Jean-Luc Houeto</name><name sortKey="Tranchant, Christine" sort="Tranchant, Christine" uniqKey="Tranchant C" first="Christine" last="Tranchant">Christine Tranchant</name></country><country name="États-Unis"><region name="Californie"><name sortKey="Zhang, Lin" sort="Zhang, Lin" uniqKey="Zhang L" first="Lin" last="Zhang">Lin Zhang</name></region><name sortKey="Espay, Alberto J" sort="Espay, Alberto J" uniqKey="Espay A" first="Alberto J" last="Espay">Alberto J. Espay</name><name sortKey="Feigin, Andrew" sort="Feigin, Andrew" uniqKey="Feigin A" first="Andrew" last="Feigin">Andrew Feigin</name><name sortKey="Gostkowski, Michal" sort="Gostkowski, Michal" uniqKey="Gostkowski M" first="Michal" last="Gostkowski">Michal Gostkowski</name><name sortKey="Jaeger, Judith" sort="Jaeger, Judith" uniqKey="Jaeger J" first="Judith" last="Jaeger">Judith Jaeger</name><name sortKey="Johns, Donald" sort="Johns, Donald" uniqKey="Johns D" first="Donald" last="Johns">Donald Johns</name><name sortKey="Maruff, Paul" sort="Maruff, Paul" uniqKey="Maruff P" first="Paul" last="Maruff">Paul Maruff</name></country><country name="Italie"><region name="Latium"><name sortKey="Stocchi, Fabrizio" sort="Stocchi, Fabrizio" uniqKey="Stocchi F" first="Fabrizio" last="Stocchi">Fabrizio Stocchi</name></region></country><country name="Canada"><noRegion><name sortKey="Di Paolo, Therese" sort="Di Paolo, Therese" uniqKey="Di Paolo T" first="Thérèse" last="Di Paolo">Thérèse Di Paolo</name></noRegion></country><country name="Suisse"><noRegion><name sortKey="Feuerbach, Dominik" sort="Feuerbach, Dominik" uniqKey="Feuerbach D" first="Dominik" last="Feuerbach">Dominik Feuerbach</name></noRegion><name sortKey="Gomez Mancilla, Baltazar" sort="Gomez Mancilla, Baltazar" uniqKey="Gomez Mancilla B" first="Baltazar" last="Gomez-Mancilla">Baltazar Gomez-Mancilla</name><name sortKey="Hockey, Hans Ulrich" sort="Hockey, Hans Ulrich" uniqKey="Hockey H" first="Hans-Ulrich" last="Hockey">Hans-Ulrich Hockey</name><name sortKey="Jakab, Annamaria" sort="Jakab, Annamaria" uniqKey="Jakab A" first="Annamaria" last="Jakab">Annamaria Jakab</name><name sortKey="Rozenberg, Izabela" sort="Rozenberg, Izabela" uniqKey="Rozenberg I" first="Izabela" last="Rozenberg">Izabela Rozenberg</name><name sortKey="Sovago, Judit" sort="Sovago, Judit" uniqKey="Sovago J" first="Judit" last="Sovago">Judit Sovago</name><name sortKey="Weiss, Markus" sort="Weiss, Markus" uniqKey="Weiss M" first="Markus" last="Weiss">Markus Weiss</name></country><country name="Espagne"><noRegion><name sortKey="Linazasoro, Gurutz" sort="Linazasoro, Gurutz" uniqKey="Linazasoro G" first="Gurutz" last="Linazasoro">Gurutz Linazasoro</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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|texte= A Placebo-Controlled Trial of AQW051 in Patients With Moderate to Severe Levodopa-Induced Dyskinesia.
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